The virus particle comes apart, releasing the viral genome. The viral RNA (vRNA) is translated into a single polypeptide that is cut into ten proteins, and the viral genome is replicated.

Further investigation by the Zhang and Lazear labs revealed that this frozen, stable RNA structure plays an important role in viral replication. They found that this particular configuration can ...

As the particles are often pseudotyped with the envelope of the vesicular stomatitis virus (VSV), the vector can serve to introduce genes into a broad range ... These features, in conjunction with ...

To test whether nSMase2 is essential for viral replication, the team inhibited the enzyme by using an antiviral compound, [phenyl(R)-(1-(3-(3,4-dimethoxyphenyl)-2, ...

Ottawa, Feb. 19, 2025 (GLOBE NEWSWIRE) -- The global viral vector and plasmid DNA manufacturing market size was valued at USD 7.19 billion in 2024 and is expected to be worth around USD 46.02 ...

ICMR-NIV director discusses India's expanding VRDL network, vaccine manufacturing, viral disease surveillance, and One Health ...

MicroRNAs function by binding to a matching piece of messenger RNA that encodes a protein and decreasing the production of that protein. Viral RNA with a base sequence complementary to that of ...

Several antiviral and anticancer drugs target the incorporation of adenine into DNA or RNA. For example, some nucleoside analog drugs, such as vidarabine and fludarabine, mimic adenine and interfere ...