Vitaxin is a humanised monoclonal IgG 1 antibody that specifically binds a conformational epitope formed by both the integrin alpha V and beta 3 subunits. It blocks the interaction of alpha V beta 3 ...

The samples were run on a BD LSRFortessa™ cell analyser and the results were analysed using FCS Express. For in vitro culturing, the plastic plates and flasks were pre-coated with Vitronectin XF™ ...

This important study examines the role of pericytes in patterning the zebrafish blood-brain barrier (BBB) and controlling its permeability. Using pdgfrb mutant zebrafish models lacking brain pericytes ...

PAI-1 (CPAI; Molecular Innovations Inc., Royal Oak, MI) or GRGDTP peptide (RGD, Sigma) were incubated in a 100 μl volume in a vitronectin-coated microtiter plate at room temperature for 2 h.

Rheumatoid arthritis (RA) is a complex autoimmune disease characterized by chronic inflammation that affects synovial tissues of multiple joints. Granzymes (Gzms) are serine proteases that are ...

Damaged endothelium exposes the underlying basement membrane, which consists of collagens, laminin, vitronectin and fibronectin, thereby providing a substratum for bacterial adherence (the initial ...

Complement activation may promote atherosclerosis. Yet, data on the to which extent complement, and more specifically the alternative complement pathway, is activated in patients with carotid ...

Computational Biology Facility, University of Liverpool, Crown Street, Liverpool L69 7ZB, U.K. Centre for Proteome Research, Institute of Systems, Molecular and Integrative Biology, University of ...

Department of Nuclear Medicine, School of Medicine & Health, Klinikum rechts der Isar, TUM University Hospital, Technical University of Munich, Ismaninger Strasse 22, Munich 81675, Germany Central ...