If you have non-small cell lung cancer (NSCLC), your doctor will recommend PD-L1 testing. This test will help your doctor understand if you can be treated with a type of cancer drug called immune ...

Background: Programed death-ligand 1 (PD-L1) is overexpressed on renal tubular and vascular epithelial cells ... The Wilcoxon matched-pairs signed-rank test was used to compare sPD-L1 levels before ...

Concordance of circulating tumor DNA and imaging surveillance in patients with urothelial carcinoma and renal cell carcinoma post-immunotherapy.

The candidate biomarkers of response to PD-1/PD-L1 blockade cancer immunotherapy were subjected to Area Under the Curve (AUC) analysis using pROC and statistical differences calculated using one ...

Genomic landscape study of esophago-gastric adenocarcinoma (EGAC) in young patients under the age of 30 years. Relationship between the number of biopsy specimens and PD-L1 positivity.

Conclusion Our results show that myeloid cells support immune evasion in pancreatic cancer through EGFR/MAPK-dependent regulation of PD-L1 expression on tumour cells. Derailing this crosstalk between ...

During a live event, Alexander I. Spira, MD, PhD, and participants NGS testing practices and the rationale behind their ...

Predicting how cancer patients will respond to treatment remains a critical challenge. Immune checkpoint inhibitors (ICIs), a ...

x² test was applied for categorical variables and Fisher test was used when the number ... We determined the concentration of the soluble fraction of the IC molecules PD-1, PD-L1 and PD-L2 in serum of ...

Anti-mouse PD-L1 Ab (or isotype IgG) was intraperitoneally injected into mice as illustrated in the figures. GraphPad Prism V.6.0 (GraphPad Software Inc) was used to analyse the data. Statistical ...