A series of substituted chalcone oxides (1,3-diphenyl-2-oxiranyl propanones) and structural analogs was synthesized to investigate the mechanism by which they inhibit soluble epoxide hydrolases (sEH).

EaStCHEM, School of Chemistry, University of St. Andrews, North Haugh, St. Andrews KY169ST, U.K.

Post-polymerization modification of incorporated monomer units focus on two types of ... (8) To avoid synthesis of the heat- and shock-sensitive azide-containing monomer, azido groups were introduced ...

Kimika Fakultatea, Euskal Herriko Unibertsitatea UPV/EHU, Donostia 20018, Spain ...

Lissencephaly is a severe neurodevelopmental disease often caused by mutations in the Dcx gene. Using a human cellular model of lissencephaly, the authors report that DCX restricts neuronal ...

The most commonly mutated ALS-linked genes are reviewed with an emphasis on disease-causing mechanisms. The cellular processes involved in ALS pathogenesis are discussed, with evidence implicating ...

Figure 1 Mechanisms of pathogen avoidance. A variety of comprehensive mechanisms are in place to regulate pathogens avoidance, which include those caused by the alteration of aerotaxis, intestinal ...

In this Review, we summarise common mechanisms driving acute and long-term side-effects and discuss monitoring strategies for radiotherapy survivors. We explore ways to mitigate toxic effects through ...

The introductory slide from the home page, reproduced below, indicates that Controlled/"Living" Radical Polymerization (CRP) procedures can be used for the preparation of copolymers, incorporating a ...