Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene. These include structural and chemical changes to the genetic material, binding of proteins to ...

Gene expression is the generation of a functional gene product from the information encoded by a gene, through the processes of transcription and translation. Gene products are often proteins ...

Copyright 2025 The Associated Press. All Rights Reserved. Chicago Chess Records producer Gene Barge attends a screening of the film “Cadillac Records,” about ...

The company raised $200 million after early findings hinted its therapy could be more potent than others like it, including Sarepta Therapeutics’ Elevidys.

While hsa-miR-32-5p exclusively regulated ECM-related genes (COL1A2 and ITGA5), NR1H2 and SNAI1 also targeted other pathways (adhesion ... The MiRGTF-net tool allows one to construct miRNA–gene–TF ...

It is widely assumed that such alleles exert small regulatory effects on the expression of cis-linked genes. However, despite the availability of gene expression and epigenomic datasets, few ...

Collins, along with Matthew Lau ’25, developed the affordable CRISPRKit to make CRISPR gene-editing technology accessible to high school students underrepresented in the sciences. The kit was ...

Transcription factors are important regulators of gene expression. The effects of human amniotic MSCs (hAMSCs ... treated group and downregulating the expression of the pro-fibrogenic genes TGF-β1, ...

Screen icon Gene Hackman turned 95 on January 30, kicking off another milestone year in the legendary actor's life. While the star has led his life away from the spotlight for the majority of the ...

Chromosome 7 COL1A2 (collagen, type 2, alpha 2) Same Chromosome 9 COL5A1 (collagen, type 5 alpha 1) Same Chromosome 2 COL5A2 (collagen, type 5, alpha 2) Same ...

Feb. 7, 2025 — A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 ...