How is a normal cell transformed into a cancerous cell? The proteins involved in cell division events no longer appropriately drive progression from one cell cycle stage to the next.
Interestingly, protein kinases phosphorylate each other as well as act on common targets. Aa Aa Aa The cell cycle allows faithful inheritance of the genetic material from mother to daughter cells.
Imagine a cancer treatment that precisely targets malignant cells, leaving healthy ones untouched. Consider, also, a cancer treatment that corrects abnormal protein synthesis to produce healthy ...
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The ICIT mechanism's ability to control protein translation at the single-cell level also offers a transformative approach to the treatment of cancers and other tissue-specific diseases.
Learn more about the high-purity GMP-grade human activin A / INHBA protein, designed for therapeutic and research ...
There are many molecules with therapeutic potential, but it can be a challenge to deliver them to the right places at the ...
Ubiquitin-specific protease 7 (USP7) is involved in DNA repair and cell cycle progression and, due to its control over the ubiquitination of key proteins, may impact oncogenes like MDM2 and c-Myc, as ...
Protein phosphorylation is a cornerstone of cellular communication, orchestrating rapid and precise responses to ...
A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...
When Xiao Wang applied to faculty jobs, many of the institutions where she interviewed thought her research proposal - to ...
Protein modifications are key to cell survival because they ensure they do what they are supposed to do in a healthy system. One vital modification involves adding sugar molecules to proteins, a ...