In this protocol, we detail a seven-stage differentiation methodology for generating pancreatic delta cells (SC-delta cells) from human pluripotent stem cells (hPSCs). In the first step, definitive ...

Stem-cell differentiation is the process by which a more specialised cell is formed from a stem cell, leading to loss of some of the stem cell's developmental potential. Stem-cell differentiation ...

Induced pluripotent stem cells (iPSCs) offer a new means of solving this dilemma, however, with iPSCs’ potential for self-renewal and pluridirectional differentiation meaning that they can be ...

Emeritus Professor of Experimental Haematology, Constanze Bonifer, wins prestigious award for advancing her field of research.

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in ... How Healthy Stem Cells Turn Into Or ...

Furthermore, within the subtypes of T/ILC/NK lymphocytes, CD4 αβ T cell was enriched in pathways like alpha-beta T cell differentiation, highlighting their crucial role in immune responses. ILCs and ...

Mar. 10, 2025 — Feral cats have long been suspects in killing native species reintroduced into Australian conservation areas. DNA testing of the carcasses puts ...

Adipose tissues, which serve as fat reserves, have been recognized as an endocrine organ. The three-dimensional (3D) ...

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review ...

A new "self-driving" microscope developed by UT Southwestern Medical Center researchers solves two fundamental challenges that have long plagued microscopy: first, imaging living cells or ...