Cyclin-dependent kinases (CDKs) are protein kinases involved in critical cellular processes, such as cell cycle or transcription, whose activity requires association with specific cyclin subunits.

Recent work has discovered the role of the cyclin-dependent kinase (CDK)-binding protein Cks1 in degrading ... the activities of cyclin-dependent kinases (CDKs) and ubiquitin-mediated, proteasome ...

CR8 inhibits all cyclin-dependent kinases (CDKs), which have multiple roles in tumor development, but it also degrades the protein cyclin K, which promotes cancer signaling pathways. Previous ...

Cell cycle re-entry of senescent breast cancer cells after CDK4/6 inhibition (CDK4/6i) constitutes a major source of disease ...

A "pocket" on the protein cyclin B is responsible for ensuring ... The reason for this lies in the cyclins' cooperation with a kinase. Kinases are responsible for phosphorylating amino acids ...