This extension builds on a 2024 agreement to define and discover biomarkers within the DNA damage response (DDR) biological space to predict the clinical benefit of one or more drugs in Debiopharm ...

This extension builds on a 2024 agreement to define and discover biomarkers within the DNA damage response (DDR) biological space to predict the clinical benefit of one or more drugs in Debiopharm’s ...

These findings emphasize the importance of DNA repair pathways in DAC response and provide potential biomarkers. A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives ...

These results suggest that MBZ causes developmental toxicity in the zebrafish retina at least partly by activating the DNA damage response, including ATM signaling, providing a potential adverse ...

Our understanding of the DNA damage responses of human cells to radiation has increased remarkably ... IR is prevalent in various aspects of daily life, causing cellular damage through multiple ...

1The University of Texas MD Anderson Cancer Center, Houston, TX. Search for other works by this author on: ...