Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory, Bldg. 1, Moscow 119991, Russia ...

These mechanisms are just beginning to ... including continued semi-conservative replication, TLS polymerization and recombination-dependent DNA repair, ensures continuation of DNA replication.

DNA damage-induced immune stimulation occurs by a variety of mechanisms including by the cGAS/STING pathway, STAT1 and downstream TRAIL pathway activation, and direct immune cell activation. Whether ...

HR mechanisms generally achieve accurate repair of DNA damage. Double-stranded breaks are repaired by HR or by end-joining mechanisms, which can be non-homologous. Broken replication forks with ...

This manuscript describes a fundamental investigation of the functioning of Cas9 and in particular on how variant xCas9 expands DNA targeting ability by an increase-flexibility mechanism. The authors ...

CBSE Class 12 Biology Sample Paper 2024-25: The Central Board Of Secondary Education has made available the latest sample paper for the current academic year 2024-25. Students can download the ...

In this Review, we summarise common mechanisms driving acute and long-term side-effects and discuss monitoring ... 52,53 Radiation is also associated with stochastic effects, which can result from DNA ...

"These findings illuminate a critical mechanism that connects local synaptic activity to the broader gene expression changes necessary for learning and memory," said Mark Dell'Acqua, professor of ...

Of course, though, testing a child's parentage based on physical features is far too subjective — that's typically where DNA tests come in. Such tests can offer a far more scientific way of ...

Research Center for Water Resources and Interface Science, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China ...

In common with type IB enzymes, topoisomerase V relaxes DNA using a controlled rotation mechanism, but the structures show that topoisomerase V accomplishes this in different manner. Overall, the ...

As a consequence, eukaryotic cells have evolved a complex signaling network of repair processes known as the DNA damage response (DDR). The importance of DNA repair mechanisms is highlighted by the ...