Cellular motility is the spontaneous movement ... gliding and swarming. Many single cells rely on beating cilia and flagella to move. Now it is shown that the core of these appendages twists ...
These include some obvious mechanical activities such as endocytosis, cell motility and membrane resealing, but also others, such as replication and transcription. Taking the motor proteins as an ...
We have characterized in vertebrates the final member of the tubulin superfamily, zeta-tubulin. In multiciliated cells, zeta-tubulin is a component of the basal foot, a centriolar appendage that ...
Motile cilia are hair-like cell extensions that beat periodically to generate fluid flow along various epithelial tissues within the body. In dense multiciliated carpets, cilia were shown to exhibit a ...
We assess the function of katanins in dividing and non-dividing cells and how their dysregulation promotes impaired ciliary signaling and defects in developmental programs (corticogenesis, ...
In contrast, postmitotic multiciliated cells (MCCs) uncouple centriole assembly from cell cycle progression and produce hundreds of centrioles in the absence of DNA replication to serve as basal ...
Most cell types express at least one member of each group and these proteins assemble into ordered apolar complexes (Fung et al., 2014). In vertebrates there are two types of cilia: (a) motile cilia, ...