The swelling was bilaterally symmetrical ... bile-duct proliferation, hepatic-cell necrosis and the presence of hyaline degeneration ("alcoholic hyaline") 9 were found. Six patients survived ...

Liver cirrhosis is a dangerous disease to have, and patients with liver cirrhosis develop swelling of the abdomen due to fluid accumulation, known as ascites, and may also experience pedal edema.

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

This suggests these cells may be useful as new therapeutic targets for various liver conditions. The work appears in the journal Immunity. The specific functions of these cells in the context of ...