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28 天
破解黑色素瘤耐药难题,CD133PD-L1癌细胞的“伪装术”被识破
【导读】基因或纳米粒子工程化巨噬细胞的采纳性转移是治疗实体瘤的一种前景广阔的细胞治疗模式。然而,其疗效并不理想,无法实现肿瘤的完全消退,而且其潜在机制仍未确定。在这项研究中,团队在小鼠黑色素瘤中发现了CD133和程序性死亡配体1上调的癌 ...
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