The US Food and Drug Administration (FDA) has approved Romvimza (vimseltinib), from Deciphera Pharmaceuticals, a kinase ...

The Fast Track designation is supported by data from a phase 2 trial that evaluated eRapa in 30 adult patients with FAP.

VANCOUVER, BC / ACCESS Newswire / February 10, 2025 / Onco-Innovations Limited (CSE:ONCO)(Frankfurt:W1H ,WKN:A3EKSZ) ('Onco' or the 'Company') is pleased to pro ...

No significant difference in the risk for MACE was observed between patients with IBD receiving JAK vs TNF inhibitors.

This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license. This work is licensed under a Creative Commons Attribution 4.0 International ...

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase first identified in a chromosomal translocation associated with some anaplastic large cell lymphomas (ALCL), a subset of T-cell non ...

The mechanistic target of rapamycin (mTOR) is a serine/threonine kinase whose activity contributes to leukemia proliferation and survival. Compounds targeting the mTOR active site inhibit ...

This study provides a comprehensive comparison of the cardiovascular safety profiles of various Tyrosine Kinase Inhibitors (TKIs) used in the treatment of Non-Small Cell Lung Cancer (NSCLC). Our ...

AI networking refers to the application of artificial intelligence (AI) technologies to network management and optimization. It involves using AI algorithms and machine learning techniques to ...

This "bi-kinase module" sensitizes the NADPH oxidase to calcium and enables synergistic activation of this enzyme, which then produces more reactive oxygen species. One of the two calcium ...

The purpose of this study was to investigate whether circulating pyruvate kinase M2 (PK‐M2) levels are elevated in the peripheral blood and to assess their association with diagnosis and prognosis in ...

N-terminal kinase exerts a cross-tissue therapeutic effect on metabolic dysfunction induced by sucrose overconsumption in rats.