Scientists are looking at a range of different drug classes, such as lysyl oxidase (LOX ... responses along multiple cellular signalling pathways that lead to a build up of fibroblasts.

This study shows that MRGPRX2 activation with substance P increased Lysyl t-RNA synthetase (LysRS) translocation to the nucleus ... MITF silencing reduced MRGPRX2-dependent calcium influx and mast ...

The Israelites were near their last encampment and would soon cross the Jordan River to enter into the promised land. Some of them had been children when, with their parents, they had left Egypt; ...

The cardiac fibroblast-to-myofibroblast differentiation and extracellular matrix collagen deposition are the hallmarks of cardiac fibrosis, which are modulated by multiple signaling pathways and ...

108 These myeloid cells are recruited from the bone marrow to the site of the tumour by distinct chemokine pathways co-opted by the tumour cells to facilitate myeloid cell attraction. TAMs may acquire ...

This valuable study investigated the role of PLECTIN, a cytoskeletal crosslinker protein, in hepatocellular carcinoma development and progression. Using a liver-specific Plectin knockout mouse model, ...

The way you personalize that experience is through this lever of career pathways. Each student has their own lever of engagement in school, but fully developing pathways helps meet the needs of a ...

These new pilots are referred to collectively by IRCC as Canada’s “Home Care Worker Immigration Pilots”. These pilot programs will replace the previous permanent residence (PR) pathways for caregivers ...

Elucidating the molecular signalling pathways that control expression of the MYCN oncoprotein and targeting these pathways with novel therapeutics is a major goal of the laboratory. We use a variety ...

At Trinity, many of our programmes offer pathways to give you the flexibility to focus or expand your areas of interest over your years at Trinity. As a Trinity student, you will have choices to make ...