Targeted therapies can specifically target CML cells while sparing healthy body cells. Tyrosine Kinase Inhibitors (TKIs) are targeted therapies that block the abnormal protein made by the CML cells, ...

MLN0128 (formerly known as INK128) is a novel, orally active mTOR kinase inhibitor currently in clinical development. Here, we evaluated MLN0128 in preclinical models of B-cell acute lymphoblastic ...

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine ... cells and will help in the selection and validation of new small-molecule inhibitors of ALK. Identification of oncogenic ALK genomic ...

1Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. 2The University of Texas MD Anderson Cancer Center, UTHealth Houston Graduate ...

Prime Video releases original new movies and shows like My Fault: London and Invincible: Season 3 for free streaming this February. Other noteworthy titles to look out for this month include ...

The February 2025 schedule for new Starz titles has tons of notable release dates lined up. All of the best titles are dropping all month long, including premieres from Starz Original series and ...

For reasons that escape us, Amazon Prime Video took an exceedingly long time to announce its lineup of original programing for February 2025. There’s no apparent reason for the delay, especially ...

Table of Contents Our top picks for February Everything new on Apple TV+ in February Last month’s top picks Although Apple TV+ has made some recent exceptions to its original content-only ...

Fans of the network know Hallmark continues to air original movies year-round — not just during the holidays — and following January’s “Winter Escape,” a new slate of “Loveuary ...

The dark skies during a new moon provide ideal conditions for spotting skywatching targets that would otherwise be outshined by moonlight. The next new moon will occur on Thursday, Feb.

Dr. Salvador, together with Dr. Claudia Valverde, from Vall d'Hebron Hospital, facilitated access to new inhibitors, which are currently undergoing testing in clinical environments. Additionally ...

However, the clinical efficacy of mitogen-activated protein kinase (MAPK) pathway inhibitors (MAPKi) for MAP2K1-mutant tumors is not well defined. We sought to characterize the genomic and clinical ...