The chromatin-bound proteome of embryonic stem cells transitioning to 2C-like cells uncovers chromatin regulators involved in heterochromatin formation.

Newly discovered brain cells count each bite before sending the order to cease eating a meal. Columbia scientists have found specialized neurons in the brains of mice that order the animals to ...

Cells were lysed with 1% SDS in 10 mM Tris, pH 7.5, and protein extracts (pRb, 10 μg; p16, 20 μg) were separated by SDS-PAGE and transferred to a nitrocellulose membrane. We stained the blots ...

This valuable study reports a chemogenetic screen for resistance and sensitivity to three cell cycle inhibitors used in the clinic ... In addition to its core catalytic subunits, mutation of the ...

Cellular senescence, a hallmark of aging, is a cellular state characterized by cell-cycle arrest, a senescence-associated secretory phenotype macromolecular damage, and metabolic dysregulation.

Figure 2: The retinoblastoma protein phosphorylation ... into normal human somatic cells does not lead to growth transformation, does not bypass cell–cycle induced checkpoint controls and ...

People with diabetes should eat as much protein as people who don't have diabetes. In a healthy diet, roughly 10% to 35% of your daily calories should come from protein. Protein itself does not have ...

Biomedical research has long focused on the complexity of cell cycle regulation and the molecular mechanisms underpinning various diseases. Recent advancements in this field have shed light on novel ...

They found that Talin-1, a protein primarily known for its role in cell adhesion at the periphery of the cell, can also be located in the cell nucleus, where the genetic material resides.

The Public Rental Board General Manager is urging residents to take better care of the flats they are living in, as many flats are being abused, leading to increased maintenance costs and higher ...

Researchers have discovered how a particular protein affects the growth and spread ... but it also highlights a potential treatment target. Cancer cells produce molecules that can be either ...