Physical activity is not only important for fitness, but also for health. This is confirmed by a new study conducted under the direction of Prof. Dr. Maximilian Kleinert at the German Institute of ...

Doses found in commercial supplements range from 10 to 1,000 mg. Calcium pantothenate and pantethine are other common forms of the vitamin. The recommended daily intake of pantothenic acid for anyone ...

PINK1 phosphorylates MIRO and activates Parkin mediated ubiquitination and degradation of MIRO. MFN1, mitofusin 1; MFN2, mitofusin 2; OPA1, optic atrophy 1; LRRK2, leucine-rich repeat kinase 2; VPS35, ...

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase first identified in a chromosomal translocation associated with some anaplastic large cell lymphomas (ALCL), a subset of T-cell non ...

Two sphingosine kinase isoforms, sphingosine kinase 1 (SPHK1) and sphingosine kinase 2 (SPHK2), synthesize S1P by phosphorylating sphingosine. While SPHK1 is a cytoplasmic kinase, SPHK2 is localized ...

One of these proteins is pantothenate kinase 4 (PanK4). To elucidate the role of PanK4 in regulating energy metabolism in skeletal muscle, Kleinert and his team utilized various genetic mouse ...

IN earlier investigations, we have demonstrated 1 that the injection of 100 µgm. of calcium pantothenate into the yolk sac of chicken eggs after incubation periods of 4 and 10 days is responsible ...