Recently, the accumulation of SCs has been implicated in the pathogenesis of pulmonary arterial hypertension (PAH), a progressive condition affecting the pre-capillary pulmonary arterial bed. PAH is ...

Correspondence to: Prof. M Levin, Department of Paediatrics, Faculty of Medicine, Imperial College of Science, Technology & Medicine, Norfolk Place, London W2 1PG, UK; m.levin{at}ic.ac.uk Neisseria ...

FGF receptors (FGFRs) are involved in the pathogenesis of cancer and skeletal disorders. Experiments in model systems have shown that FGFR-specific inhibitors may be valuable in treating multiple ...

The basic pathophysiology of both disorders is complex and involves metabolic, inflammatory and bioenergetic alterations. It is unclear at present whether CIP and CIM are distinct entities ...

The structural and functional abnormalities that lead to cardiac death are coronary artery disease and left ventricular abnormalities related to remodelling (left ventricular hypertrophy, left ...

We discuss the pathophysiology of clinically stable COPD and examine the impact of acutely increased expiratory flow limitation on the compromised respiratory system. Finally, we review the chain of ...

Is our understanding of the pathogenesis of Wilson's disease increased? We have found that a concentration of hepatic copper greater than 250 μg per gram dry weight is virtually necessary and ...

US President Donald Trump criticized $21 million funding for voter turnout in India and $29 million to strengthen Bangladesh's political landscape. He questioned the allocation of such substantial ...

This word has appeared in 78 articles on NYTimes.com in the past year. Can you use it in a sentence? By The Learning Network This word has appeared in three articles on NYTimes.com in the past ...

Purpose: An overview of hyponatremia is provided, including its pathophysiology, clinical manifestations, signs and symptoms, and treatment, particularly with arginine vasopressin (AVP)-receptor ...

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