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把“磷”换成“硫”,发了一篇Science,这次是中国青年学者担任一作!
在有机化学中,构建三维结构对于理解分子的立体化学和开发新型药物具有关键作用。传统的有机合成方法大多集中在二维芳香族化合物的构建上,而三维结构的合成则相对较少被探索。然而,三维结构的分子在药物设计中具有独特的优势,因为它们能够更好地模拟生物体内的天然产物和药物靶点的三维构象。例如,像立方(cubane)、螺 ...
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