It is a multi-stage disease with the maldevelopment and/or dysfunction of distinct trophoblast lineages of the placenta at the center of the disease. Villous and extravillous trophoblast (EVT) ...

Results We found that OA progressed by both top-down calcification at the joint surface and bottom-up calcification at the osteochondral interface. The top-down calcification process started with ...

Vascular calcification is a detrimental aging pathology markedly accelerated in patients with chronic kidney disease. Prelamin A is a biomarker of vascular smooth muscle cell aging that accelerates ...

This is the first step towards placenta digital twins. Armita Najmi, Ph.D. candidate in Grande Gutiérrez's lab and lead author of the paper said, "Our computational study provides practical ...

The concave zone of papillary calculi can contain a range of calcified lesions, from little HAP residues to typical well-developed HAP plaques, also known as Randall's plaques. The morphology of ...

heart valve calcification, placental calcification, nephrolithiasis, cholecystolithiasis, type III chronic prostatitis/chronic pelvic pain syndrome, and testicular microlithiasis. Electron microscopy ...