The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and ...

This content introduces the physiological and pathological importance of protein kinases, kinase inhibitors approved for ...

Cystic fibrosis is a life-threatening disease predominantly with respiratory symptoms. Most of the subjects with the disease harbor the F508del variant in the CFTR gene that causes the protein to ...

Your body produces the enzyme creatine kinase (CK) or creatine phosphokinase to keep your muscles functioning properly. Healthcare providers use the CK test to check levels of this protein in your ...

Melbourne-based scientists have, for the first time, discovered how to "switch off" a molecule which is one of the top ...

E1s and E2s first work generically across the cell to activate and prepare ubiquitin for attachment. E3 ligases then ensure that the tag is added to the right protein; as such, hundreds of specific ...

Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including ...

BYU Professor David Thomson is working to understand a chemical pathway in human muscles that may explain the effects of exercise.

Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high ...