E1s and E2s first work generically across the cell to activate and prepare ubiquitin for attachment. E3 ligases then ensure that the tag is added to the right protein; as such, hundreds of specific ...

The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and ...

Nurix Therapeutics, Inc. stock slid 40% after promising NX-5948 results in CLL. NX-5948 shows efficacy in heavily pre-treated ...

Researchers identified an enzyme that helps Plasmodium-infected red blood cells adhere to the placenta, providing molecular ...

Furthermore, they have demonstrated that it is possible to reprogram other cancer cells to become dependent on this enzyme – ...