Structures of some of the most important benzodiazepine derivatives commercially available. All reagents and solvents were used as purchased from Sigma-Aldrich (São Paulo, Brazil) without further ...

The research and development on tumor-targeted drug delivery systems has seen increasing interest due to their potential to improve some important therapeutic issues, such as poor response to ...

Department of Chemistry, Engineering Center of Catalysis and Synthesis for Chiral Molecules, Fudan University, 220 Handan Road, Shanghai 200433, P. R. China Shanghai Engineering Research Center of ...

Department of Chemistry and Biochemistry, University of California Santa Barbara, Santa Barbara, California 93106, United States Biomolecular Science and Engineering Program, University of California ...

Traumatic brain injury (TBI) represents a significant global public health issue, with effective management posing numerous challenges. The pathophysiology of TBI is typically categorized into two ...

In this case, the Onsager radius a (0.68 Å) was taken as half the average distance between the 4-methoxyphenylaniline (-OCH3) in the donor moiety and the imine nitrogen carbon of the pyrazine acceptor ...