Researchers from Morphic Therapeutic Inc. and affiliated organizations published data from a study that aimed to assess the potential of using arginylglycylaspartic acid (RGD) integrins for the ...
A new review published in Genes & Diseases explores the multifaceted role of FAM20C, a Golgi protein kinase, in disease ...
HMME can serve as sonosensitizers to produce ROS (e.g., singlet oxygen) via US stimulation. The RGD peptide is well recognized as a particular binding site for integrin receptors, which are key ...
Department of Nuclear Medicine, School of Medicine & Health, Klinikum rechts der Isar, TUM University Hospital, Technical University of Munich, Ismaninger Strasse 22, Munich 81675, Germany Central ...
4 Biomaterials used in MSCs delivery of endometrial regeneration The RGD domain (Arg-Gly-Asp) is a well-known integrin-binding site that facilitates cell adhesion, migration and signal transduction in ...
Figure 3: K14.MYC2 primary keratinocytes exhibit a defect in migration. Figure 4: K14.MYC2 epidermis exhibits reduced staining for β1 integrin.
A substantial and persuasive body of data now exists that supports the view that integrin alpha V beta 3 plays a critical part in activated macrophage dependent inflammation, osteoclast development, ...
Integrins are very attractive therapeutic targets in oncology. The anti-tumor mechanisms of integrin-targeting drugs have been validated both in vitroand in vivo. Integrin-targeting drugs are ...
Department of Chemistry, King’s College London, Britannia House, 7 Trinity Street, London SE1 1DB, U.K.