Protein phosphorylation is a cornerstone of cellular communication, orchestrating rapid and precise responses to ...
Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.
Roles of membrane pores, channels, receptors, and transporters in physiology, systems, and regulation • The correlation of membrane protein structures and dynamics to the molecular mechanisms that ...
SEC-seq is a single-cell method linking the secretion of a target protein to the cell’s transcriptome. Nanovials isolate cells and capture their secretions, and oligonucleotide-labeled ...
Kinases are enzymes that catalyze the addition of a phosphate group (PO43−) to substrates, usually proteins ... but the design of highly selective kinase inhibitors remains challenging.
A neuroanatomical minimal network model was revisited to elucidate the mechanism of salt concentration memory-dependent chemotaxis observed in Caenorhabditis elegans. C. elegans memorizes the salt ...