These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...

Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

Protein phosphorylation is a cornerstone of cellular communication, orchestrating rapid and precise responses to ...

Despite the established links between inflammation and cancer development, the effects of inflammatory signaling on cancer ...

CIRBP Family, Tumors, Molecular Mechanisms, RNA-Binding Proteins, Cellular Stress Share and Cite: Cai, Y. , Wang, T. and Zhan ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Besides this, there are emerging findings that myeloid cells could be involved in tumor angiogenesis. In this article, we address the role of tyrosine kinase inhibitors in tumor immunology by ...

HMGA proteins have a crucial role in cell transformation ... mitogenic pressure and the inability to proceed through the cell cycle 21. The different cellular context might account for the ...

The immune system is made up of many interdependent parts, including lymphoid organs, cells, and cytokines, which play important roles in identifying, repelling, and eliminating pathogens and other ...

A "pocket" on the protein ... cell division when the pocket loses its shape and can no longer dock onto the substrate." The reason for this lies in the cyclins' cooperation with a kinase.

SIRT6, which belongs to the sirtuin family of NAD + -dependent deacetylases, has emerged as an important player in encouraging cancer cells to survive under oxidative stress, confirming its role in ..