BCMA Stimulates plasma cell ... B cells have a role in the regulation of CNS inflammation Autoantibodies against glycolipids and glycoproteins can induce demyelination within the PNS T-cell ...

Researchers at the Francis Crick Institute have shown that the entry of water into immune cells, such as T cells, is a key requirement for their activation and proliferation when responding to threats ...

As noted above, stellate cell activation is the central event in ... metalloproteinases has been identified that are calcium-dependent enzymes which specifically degrade collagens and ...

The immune response consists of a finely-tuned program, the activation of which must be coupled with inhibitory mechanisms whenever ... mobilization of co-stimulatory and co-inhibitory signaling in ...

A “complete eradication” of B cells with chimeric antigen receptor T-cell therapy is responsible for the long-term, drug-free remission from autoimmune diseases observed after treatment ...

T cell engagers are antibodies that are engineered to recognize and kill harmful cells, be it tumor cells in the case of cancer or autoreactive cells in the case of autoimmune diseases. They achieve ...

Follicular regulatory T (Tfr) cells modulate germinal center T and B cell responses ... Here authors show that activation of the downstream WNK1 kinase causes water entry into the cells, which ...

In collaborative work, Trethera and the Peter Clark Lab at UCLA have shown that when autoreactive T and B cells divide, they activate the TRE-515 target dCK. In those abnormally activated cells, dCK ...

T-cell lymphoma is a type of non-Hodgkin lymphoma. Non-Hodgkin lymphomas either begin in B cells or T cells — T-cell lymphomas account for less than 15 percent of all non-Hodgkin lymphomas.

Cellular unjamming is the collective fluidization of cell motion and has been linked to many biological processes, including development, wound repair, and tumor growth. In tumor growth, the ...