Systemic sclerosis, also termed scleroderma, is a multisystem connective tissue disease involving autoimmunity, inflammation, fibrosis and vasculopathy. The clinical presentation of systemic ...

Systemic sclerosis (SSc; scleroderma) is a heterogeneous disease whose pathogenesis is ... 5), fingertip lesions (weighted 16 if pitting scars or 9 if digital ulcers), finger flexion contractures ...

Among the total systemic sclerosis cohort, 14% of individuals were categorized as frail and 53% as prefrail, with frailty status linked to an increased risk for mortality. Frailty, a clinical syndrome ...

Acute and chronic renal diseases remain common complications of systemic sclerosis. Although treatment for acute scleroderma renal crisis may arrest the rapid progression of renal disease ...

Macular telangiectasia, sometimes referred to as idiopathic juxtafoveal macular telangiectasia, is a disease that affects the part of the eye called the macula, causing degradation or loss of central ...

This study aimed to employ a global antibody profiling strategy to identify novel antibodies and investigate their association with systemic sclerosis (SSc). Methods We implemented this strategy by ...

Prenatal and early life sun exposure is associated with a lower risk for relapse in childhood-onset MS, new findings suggest, but investigators say more research is needed.

If you’ve been diagnosed with multiple sclerosis (MS), it’s time to start exploring treatment options. You’ve got a lot of them, everything from disease-modifying therapies and drugs that help manage ...

“We have the first device to treat macular telangiectasia type 2, which has been through the clinical trial program, and the long-term results up to 9 years find that it is still relatively well ...

However, not everyone with MS will have complications. Multiple sclerosis (MS) is a chronic (long-term) condition with symptoms that vary from person to person. With proper management of symptoms ...

The scientific landscape surrounding amyotrophic lateral sclerosis (ALS) continues to shift as the number of genes associated with the disease risk and pathogenesis, and the cellular processes ...