A graphical abstract summarizes the approach. It is prohibited to disintegrate and or reuse individual elements of the graphical abstract, including icons, pictograph, stock images, and/or ...

Ryotaro Hashizume and colleagues use the CRISPR-Cas9 gene editing system to cleave the third chromosome in previously generated trisomy 21 cell lines derived from both pluripotent cells and skin ...

Down syndrome is a trisomy in which there are three 21st chromosomes. The arrangement would be 47XY (+21) or 47XX (+21) depending on whether the child was male ... Klinefelter syndrome occurs due to a ...

2025年2月18日，国际知名期刊《PNAS ...