The RNA viruses replicate as complex distributions of closely related genomes termed viral quasispecies. The behavior of the evolving quasispecies and its response to selective pressures such as ...

Let's back up one on viral dynamics and first look at viral quasispecies, which preceded viral dynamics. Although modeled precisely on, and of relevance to, viruses cultured ex vivo, the concept ...

HIV drug susceptibility tests can evaluate either the genotype or phenotype of the predominant viral quasispecies. The HIV genotype refers to the actual DNA sequence of the virus; the phenotype ...