Chromatin - Wikipedia
In general, there are three levels of chromatin organization: DNA wraps around histone proteins, forming nucleosomes and the so-called beads on a string structure (euchromatin). Multiple …
Organization and function of the 3D genome - Nature
2016年10月14日 · We examine the different levels of chromatin organization — from chromatin loops to chromosome territories — and we address the molecular mechanisms responsible for …
Biology of Chromatin - Introduction to Epigenetics - NCBI Bookshelf
2021年3月24日 · This chapter provides an introduction to chromatin. We will examine the organization of the genome into a nucleosomal structure. DNA is wrapped around a globular …
Establishment and function of chromatin organization at …
2023年4月5日 · Here, using genome-scale biochemical reconstitution with approximately 300 replication origins, we screened 17 purified chromatin factors from budding yeast and found …
Chromatin organization: form to function - PubMed
Recent developments in technology have made it possible to create high resolution genome-wide maps of histone marks, DNA binding proteins and physical interactions along genomic …
Chromatin Organization - Cell Press
2011年8月5日 · By clustering the CTCF-formed chromatin loops based on their histone modification patterns, the authors uncover five distinct classes of CTCF-associated chromatin …
Chromosomes and Chromatin - The Cell - NCBI Bookshelf
The organization of chromatin in nucleosomes. (A) The DNA is wrapped around histones in nucleosome core particles and sealed by histone H1. Nonhistone proteins bind to the linker …
Spatial organization of chromatin domains and compartments in …
2016年7月21日 · In eukaryotic cells, DNA is packaged into a complex macromolecular structure called chromatin. Wang et al. have developed an imaging method to map the position of …
Organization of Chromatin by Intrinsic and Regulated Phase Separation
Eukaryotic chromatin is highly condensed but dynamically accessible to regulation and organized into subdomains. We demonstrate that reconstituted chromatin undergoes histone tail-driven …
DNA Packaging: Nucleosomes and Chromatin - Nature
Chromosomal DNA is packaged inside microscopic nuclei with the help of histones. These are positively-charged proteins that strongly adhere to negatively-charged DNA and form …