The aldol reaction (aldol addition) is a reaction in organic chemistry that combines two carbonyl compounds (e.g. aldehydes or ketones) to form a new β-hydroxy carbonyl compound. Its …

In organic chemistry, aldol reactions are acid- or base-catalyzed reactions of aldehydes or ketones. Aldol addition or aldolization refers to the addition of an enolate or enolation as a …

2015年5月15日 · In this work, a kinetic model is developed for the acid–base cooperative catalysed aldol condensation reaction. The focus is on the effect of the structure and base …

2024年9月29日 · Members of a new class of bifunctional amino quaternary phosphonium salts have been synthesized and utilized as catalysts in aldol condensation reactions, as …

2001年5月9日 · Structure-based catalyst screening identified l-proline and 5,5-dimethyl thiazolidinium-4-carboxylate (DMTC) as the most powerful amino acid catalysts for the …

2022年4月3日 · During the past two decades, new insights have driven the development and optimization of aminated materials as aldol condensation catalysts. Amines, either primary or …

2020年4月24日 · Here, we unraveled the deactivation of secondary amines by undesired aldol reaction. Mechanistic studies with peptide and prolinol silyl ether catalysts showed the …

2024年7月16日 · A useful carbon-carbon bond-forming reaction known as the Aldol Reaction is yet another example of electrophilic substitution at the alpha carbon in enolate anions. The …

2021年1月15日 · The experimentally observed effects of water, and the effects of silanol groups, on the liquid-phase amine-catalyzed aldol reaction of acetone with 4-nitrobenzaldehyde have …

The asymmetric aldol reaction of an enolate or enolate equivalent with an imine is a reaction of established synthetic importance for the synthesis of chiral amines in general and b -amino …