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  1. Department of Defense (DoD) Impact Level 4 (IL4)

    2023年4月4日 · What Azure services are covered by DoD IL4 PA and in what regions? To find out what services are available in Azure Government, see Products available by region. For a list …

  2. Interleukin 4 - Wikipedia

    The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (T h 0 cells) to T h 2 cells. Upon activation by IL-4, T h 2 cells subsequently produce additional IL-4 in …

  3. Recent advances in understanding the role of IL-4 signaling

    STAT6 is so vital for the actions of IL-4 that Stat6 -deficient mice phenocopy many of the defects observed with Il4 - or Il4ra -deficient mice (e.g., related to Th2 differentiation and Ig class switch).

  4. Recent advances in understanding the role of IL-4 signaling

    2021年9月7日 · Interleukin-4 (IL-4) is a four-α-helical bundle type I cytokine with broad pleiotropic actions on multiple lineages. Major actions of IL-4 were initially discovered for B and T cells, …

  5. IL4 Gene - Interleukin 4 - GeneCards

    2024年12月25日 · IL4 (Interleukin 4) is a Protein Coding gene. Diseases associated with IL4 include Schistosomiasis and Allergic Disease. Among its related pathways are MIF Mediated …

  6. Interleukin-4: A Cytokine to Remember - PubMed Central (PMC)

    IL-4 plays important roles in a myriad of cellular events, making it difficult to study its effects, particularly in vivo, on any one system. Although this review focuses on its neurological …

  7. The IL-4 receptor: signaling mechanisms and biologic functions

    Interleukin-4 is a multifunctional cytokine that plays a critical role in the regulation of immune responses. Its effects depend upon binding to and signaling through a receptor complex …

  8. Regulation of IL4 gene expression by T cells and therapeutic ...

    2003年7月1日 · Acute expression of the IL4 gene by differentiated T H 2 cells is regulated by many positive and negative inducible transcription factors, such as nuclear factor of activated …

  9. IL-4 in the Brain: A Cytokine To Remember - American Association …

    2012年11月1日 · Human neurological cancer cells express interleukin-4 (IL-4) receptors which are targets for the toxic effects of IL4-Pseudomonas exotoxin chimeric protein.

  10. Evolution and function of interleukin-4 receptor signaling in

    2020年3月6日 · A single Il4 / Il13 -related gene was found in spotted gar (Lepisosteus oculatus), an example of a bony fish that only went through two rounds of WGD, whereas two Il4 / Il13 …

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